Tuesday, August 12, 2008

Ovine toxoplasmosis: transmission, clinical outcome and control

Parassitologia. 2007 Dec;49(4):219-21

Ovine toxoplasmosis: transmission, clinical outcome and control

Buxton D, Maley SW, Wright SE, Rodger S, Bartley P, Innes EA.

Moredun Research Institute, Edinburgh, Scotland, UK. david.buxton@moredun.ac.uk

Toxoplasma gondii is a significant cause of abortion in sheep. Infection is picked up from the environment and if initiated during pregnancy may cause fetal mortality. Infected sheep remain persistently infected with tissue cysts in brain and muscle (meat), and are also immune and would not be expected to abort again. The live tachyzoite vaccine (Toxovax) protects against abortion and this allows the suggestion that it may also reduce or prevent tissue cyst development in muscle. If this were so it raises the question of whether the vaccine could be used to make meat safer for human consumption.

PMID: 18689230 [PubMed - in process]

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