Thursday, September 11, 2008

Securing mucosal borders-migrant monocytes to the rescue

Cell Host Microbe. 2008 Sep 11;4(3):192-4

Securing mucosal borders-migrant monocytes to the rescue

Yap GS, Iwasaki A.

Center for Immunity and Inflammation, Department of Medicine, UMDNJ-New Jersey Medical School, Newark, NJ 07101, USA.

Gr1(+) "inflammatory" monocytes are emerging as key players in the innate immune response to infection and vaccination. In a recent issue of Immunity, Dunay et al. (2008) report a surprisingly crucial role for inflammatory monocytes in mucosal resistance to the parasitic agent Toxoplasma gondii.

PMID: 18779043 [PubMed - in process]

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